WebDec 19, 2016 · Among the mTORC 1 downstream molecules, the change in S6 phosphorylation ( pS 6) showed the most significant correlation with sensitivity. Using xenograft models derived from highly sensitive and resistant cell lines, we found specific reduction of pS 6 in xenografts from highly sensitive cell lines after 6 h of treatment with … WebDec 1, 2024 · The ribosomal protein S6 is a downstream signalling protein in the PI3K pathway involved in protein synthesis and cell proliferation 27 and it has been recently …
Frontiers Porcine Plasmacytoid Dendritic Cells Are Unique in …
WebMar 11, 2024 · The expression of phosphorylated ribosomal protein S6 (pS6) was analyzed after 3 and 6 h. For intracellular cytokine staining, Brefeldin A (GolgiPlug, BD Biosciences, San Jose, CA, USA) was added to microcultures at a final concentration of 1 µg/ml after 2 h of stimulation for an additional 4 h. WebPhospho-S6 Ribosomal Protein (Ser235/236) Antibody detects endogenous levels of ribosomal protein S6 only when phosphorylated at serine 235 and 236. This antibody does not detect ribosomal protein S6 … onorm m5873-1
Phospho-S6 Ribosomal Protein (Ser235/236) Antibody
WebDownload scientific diagram Kaplan-Meier plots by molecular marker status. The vertical tick marks represent patients censored for survival at the time of analysis. P-values are based on the ... WebDec 1, 2024 · The ribosomal protein S6 is a downstream target of the phosphatidylinositol 3-kinase (PI3K) pathway involved in protein synthesis and cell proliferation. In previous studies, low phosphorylated S6 (pS6) immunoreactivity was significantly correlated with longer progression-free survival (PFS) and overall survival (OS) in PM patients. WebPhosphorylation of S6 Protein as a Potential Biomarker in Surgically Treated Refractory Epilepsy The tuberous sclerosis complex (TSC), focal cortical dysplasia IIB (FCD IIB), and hemimegalencephaly (HME) exhibit similar molecular features that are dependent on the hyperactivation of the mTOR pathway. on or of difference