Phospho s727

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August undefined, 2024

WebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09 Purification ProA affinity purified; Applications WB, ICC/IF, IHC, IP; Species Reactivity Hu, RtMs; Immunogen Description Synthetic phospho-peptide corresponding to residues surrounding Ser727 of human STAT3.; Alternative Names … WebThis protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.

STAT3 phosphorylation at Ser727 and Tyr705 differentially

WebNov 13, 2024 · Phospho-S727 Stat3 localizes in mitochondria. Recently, Larner and Levy groups described that phospho-Stat3 S727, but not phospho-Stat3 Y705, led to the … WebSynthetic peptide within Human STAT1 (phospho S727). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Database link: P42224 ray ban made in italy original price

Human/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA

WebHuman Phospho-STAT3 (S727) Antibody Summary. Detects human STAT3 when phosphorylated at S727 in Western blots. Lyophilized from a 0.2 μm filtered solution in … WebPhospho-Stat1 (Ser727) Antibody detects endogenous levels of Stat1α only when phosphorylated at Ser727. This site is deleted in Stat1β. This antibody does not … WebCitations: (293) The Phospho-Stat3 (Ser727) Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody to STAT3. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-Stat3 (Ser727) Antibody has been validated for the following applications: Precipitation, ChIP, Immunoprecipitation, and Western Blot. ray ban manchester

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STAT3 Serine 727 Phosphorylation: A Relevant Target to

WebHuman/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA. Be the first to review this product . RayBio® Human/Mouse Phospho-Stat 1 (S727) and Total Stat 1 ELISA Kit. This assay semi-quantitatively measures phosphorylated Stat 1 (Ser727) and Total Stat 1 in lysate samples. MANUAL / SDS. As low as $567.00. Size WebApr 23, 2002 · Phosphorylation of S727 in Stat1 can be induced by a variety of stimuli such as IFN-γ, lipopolysaccharide, and UV, and p38 mitogen-activated protein (MAP) kinase has been implicated in lipopolysaccharide- or UV-induced phosphorylation of S727 in Stat1 ( … simple php code for websiteWebMay 4, 2024 · Serine kinases play a more nuanced role in regulating Stat3 due to direct Stat3 activation through S727 phosphorylation ( 16) by kinases such as mTOR ( 7) and others, which also have the potential for competing inhibitory effects from parallel downregulation of Stat3 tyrosine phosphorylation pathways ( 17 ). simple phowa practice

"WebPhospho-STAT1 (Ser727) Antibody (PA5-97355) in ICC/IF Immunofluorescence analysis of Signal transducer and activator of transcription 1-alpha/beta was performed using 70% confluent log phase HeLa cells treated with IFN gamma (100 ng/mL for 30 minutes). " - Phospho s727

Phospho s727

STAT3 phosphorylation at Ser727 and Tyr705 differentially

WebSep 30, 2008 · S727 phosphorylation enhances the transcriptional activities of Stat3, whereas mutations of S727 compromise Stat3 transactivational activity and downstream effects ( 8 ). Cooperation of both tyrosine and serine phosphorylation is necessary for full activation of Stat3 ( 4 ). WebHSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway (2,3). Phosphorylation of HSP27 causes a …

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WebOct 30, 2006 · In vivo analyses of S727 of Stat1 and Stat3 using knock-in mouse models showed that S727 plays important physiological roles [13], [14]. However, the biochemical function underlying the physiological importance of the phospho-serine and conserved LPMSP motif is not completely understood.

WebStat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor comp WebFeb 5, 2024 · TGFβ is the prototype of a large family of pluripotent cytokines with diverse effects on cellular proliferation, tumor growth, apoptosis, differentiation, fibrosis, anti-inflammation, and embryo development [1,2,3,4,5].The competence of TGFβ cytokine signaling plays an important role in determining lineage acquisition in cells of …

WebDec 1, 2024 · Besides, phospho-TBK1 S511 was not induced by AKT1 but augmented upon the suppression of AKT activity, ... Rabbit monoclonal anti- STAT1 (phospho S727) Cell Signaling Technology: Cat#8826; RRID: AB_2773718: Mouse monoclonal anti-Myc Tag: Cell Signaling Technology: Cat#3739, RRID: AB_10889248: WebWestern blot - Phospho-STAT3-S727 Rabbit pAb (AP0474) Western blot analysis of extracts of various cell lines, using Phospho-STAT3-S727 antibody (AP0474) at 1:1000 dilution.HepG2 cells and C6 cells were treated by PMA/TPA (200 nM) at 37℃ for 30 minutes after serum-starvation overnight.HepG2 cells were treated by CIP (20uL/400ul) at 37℃ for ...

WebHere, we studied the role of STAT3 activation on tyrosine 705 (Y705) and serine 727 (S727) in glioma radioresistance. This study explored STAT3 phosphorylation on Y705 (pSTAT3-Y705) and S727 (pSTAT3-S727) in glioma cell lines and in clinical samples. Radiosensitizing effect of STAT3 activation down-modulation by Gö6976 was explored.

WebFlow cytometry of Phospho-Stat1 (Ser727) using U937 cells. Samples were incubated in monoclonal Phospho-Stat1 (Ser727) antibody ( Product # MA5-37074 ). Images correspond with the following conditions: negative control (blue), stained untreated (red), treated with IFNa IL-4 and pervanadate (green). Product Details Product Specific Information simple php class exampleWebHuman Phospho-STAT3 (S727) Antibody Summary Species Reactivity Human Specificity Detects human STAT3 when phosphorylated at S727 in Western blots. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human STAT3 S727 site Accession # P40763 Formulation simple php backdoorWebDec 21, 2012 · We used immunohistochemistry with phospho-specific antibodies to look at the presence of activated JAK2 and STAT3 in human tissues, BTSCs, and tumors from orthotopic xenografts. We found strong staining of the cell membrane for phosphorylated Y1007/1008 JAK2 and staining of the nucleus for phosphorylated Y705 and S727 STAT3 … simple photosynthesis diagramWebUsing a combination of HepG2-stat3-knockdown cells reconstituted with various STAT3 mutants and protein kinase inhibitors, we showed that phospho-S727 has an intrinsic … simple photo themeWebPhospho S727 (2) Phospho S51 (1) Asymmetric DiMethyl R3 (1) MonoMethyl R26 (1) Phospho S380 (1) Symmetric DiMethyl R2 (1) Phospho S33 (1) Acetyl K23 (1) Asymmetric DiMethyl R8 (1) DiMethyl K14 (1) MonoMethyl R17 (1) MonoMethyl R8 (1) MonoMethyl R3 (1) Phospho S455 (1) Phospho Thr4 (1) Phospho S259 (1) Phospho S957 (1) Phospho … simple php forms from w3 schoolsWebProduct Name Phospho-STAT3(S727) Rabbit mAb; Host Species Rabbit ; Clonality Monoclonal ; Clone No. SY24-09; Purification ProA affinity purified; Applications WB, … simple php authenticationWebJan 15, 2001 · S727 phosphorylation of STAT1 in interferon-γ (IFN-γ)-treated mouse fibroblasts occurred without a need for p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinases 1 and 2 or c-Jun kinases, and required both an intact SH2 domain and phosphorylation of Y701. simple php form validation