WebDec 10, 2024 · The trajectory of B cell development goes through subsequent steps governed by complex genetic programs, strictly regulated by multiple transcription factors. Interferon regulatory factor 4 (IRF4) regulates key points from pre-B cell development and receptor editing to germinal center formation, class-switch recombination and plasma cell … WebApr 8, 2024 · For testing of putative cross-reactive antibody candidates, recombinant fusion proteins of porcine Blimp-1, IRF4, or Pax5 with a C-terminal FLAG tag were generated and expressed in HEK293T cells. RNA extraction and cDNA synthesis of lymphocytes isolated from lung tissue (Blimp-1) or PBMC (IRF4, Pax5) were done as described by Lagler et al. .
Gene expression profiling-based classifier of IG/IRF4-positive …
WebIRF-4 is a member of the interferon regulatory factor (IRF) family of transcription factors, which were first identified as being involved in the expression of interferon-induced genes. … WebMar 21, 2024 · IRF4 (Interferon Regulatory Factor 4) is a Protein Coding gene. Diseases associated with IRF4 include Skin/Hair/Eye Pigmentation, Variation In, 8 and Whipple … greater western water head office address
3662 - Gene ResultIRF4 interferon regulatory factor 4 [ (human)]
WebSep 1, 2013 · Breakapart FISH for the DUSP22-IRF4 locus on 6p25.3 demonstrates abnormal separation of the red and green signals in the cell in the lower left (arrows). A cell with a normal signal pattern (two fusion signals, f) is seen in the upper right. WebBIRF4 (Blood Sample): Fluorescence in Situ Hybridization (FISH) is performed uisng IRF4 break-apart FISH probe to detect IRF4 rearrangement from leukemic blood samples. Click … WebApr 2, 2024 · The lymphoma cells displayed one fusion signal and one break-apart signal, confirming the presence of IRF4 chromosomal breakpoint. Prevalence of 11q aberration in morphological BL/DLBCL/HGCBL From 2014 to 2024, 102 patients with morphological BL/DLBCL/HGBCL were identified (71 BL, 11 HGBCL unclassifiable and 20 de novo DLBCL). greater western water grease trap