WebThe fungus Cryptococcus neoformans is the causative agent of cryptococcosis, a disease that is uniformly lethal unless treated with antifungal drugs, yet current regimens are … WebSep 17, 1998 · It is likely that there are many subtle virulence factors in fungi, such as the simple ability to survive and grow within the host, that are important to their ability to be …

Cryptococcus neoformans capsule biosynthesis and regulation

WebJun 3, 2014 · Why Cryptococcus neoformans has this remarkable tropism for the CNS is not clear. Recent research on cerebral pathogenesis of C. neoformans revealed a predominantly transcellular migration of cryptococci across the brain endothelium; however, the identities of key fungal virulence factors that function specifically to invade the CNS … biogenetics biology

Full article: The capsule of Cryptococcus neoformans - Taylor

WebThe polysaccharide capsule of Cryptococcus is a major virulence factor, and in addition to surrounding the organism, it is also released into the environment. Cryptococcus is believed to enter the body through the lung causing pulmonary disease, but because of its neurotropic nature, the central nervous system is a major target organ. WebThe polysaccharide capsule of Cryptococcus is a major virulence factor, and in addition to surrounding the organism, it is also released into the environment. Cryptococcus is believed to enter the body through the lung causing pulmonary disease, but because of its neurotropic nature, the central nervous system is a major target organ. The major ... WebApr 1, 1999 · As reviewed by Kozel [8], the pathogenesis of cryptococcosis involves several virulence factors, which determine the increased survival of the yeast in the host, and … biogenetics clinical research corp